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N-Phenylethanamide

N phenylethanamide

Posted on February 4, 2023February 4, 2023 By Admin 1 Comment on N phenylethanamide

Table of Contents

  • The Introduction for n phenylethanamide: 
  • The Structure and Properties of N-Phenylethanamide:
  • The Molecular Structure of n phenylethanamide:
  • The Physical Properties of n phenylethanamide:
  • The chemical properties of n phenylethanamide: 
  • The Synthesis of N-Phenylethanamide:
  • The Uses of N-Phenylethanamide: 

The Introduction for n phenylethanamide: 

N-Phenylethanamide, also known as N-phenylacetamide, is an organic compound and an amide derived from the aromatic compound benzene and acetic acid. 

It is a white crystalline solid that is slightly soluble in water, alcohol, and ether. It is used as an intermediate in the synthesis of pharmaceuticals, dyestuffs, and other organic compounds. 

It is also used as a reagent for the synthesis of other organic compounds. It is a versatile intermediate and is used in a wide variety of reactions. 

It can be used as a catalyst in organic synthesis, as a reagent for the generation of aryl halides, and as a reagent for the synthesis of aryl amines and aryl sulfonamides. 

It is also used as a coupling reagent in peptide synthesis. It has been used in the synthesis of various drugs and is a common starting material in organic synthesis.

The Structure and Properties of N-Phenylethanamide:

N-Phenylethanamide, also known as N-phenylacetamide, is an organic compound with the molecular formula C8H9NO. It is a white crystalline solid with a melting point of 86-88 °C and a boiling point of 183 °C. 

It is insoluble in water but soluble in most organic solvents. The molecule consists of a benzene ring attached to an amide group. The amide group consists of a nitrogen atom bound to a carbon atom which is also bound to an oxygen atom. 

This makes the molecule polar, with the nitrogen and oxygen atoms having partial negative charges and the carbon atom having a partial positive charge. N-Phenylethanamide has a high degree of stability, making it a useful intermediate in organic synthesis. 

It can be used to prepare substituted anilines, amides, and carboxylic acids. It can also be used to make esters, amines, alkylamines, and other compounds. The molecule also has some biological activity. 

It has been shown to have antimicrobial activity against certain bacteria and fungi. It also has insecticidal activity, as well as being a potential anti-cancer agent. N-Phenylethanamide can be synthesized from aniline and acetic anhydride. 

It can also be synthesized from benzaldehyde and ammonia. The reactivity of the amide group can be modified by adding different substituents to the benzene ring. This makes it a useful building block for the synthesis of more complex compounds.

N-Phenylethanamide
N-Phenylethanamide

The Molecular Structure of n phenylethanamide:

N-Phenylethanamide, also known as N-phenylacetamide, is a white crystalline solid molecule containing a carbonyl and an amide functional group. It can be synthesized from ethanamide and phenylmagnesium bromide, and it can also be synthesized from the reaction of phenylacetic acid and ammonia. 

At the molecular level, N-phenylethanamide consists of a single carbon atom surrounded by four other atoms: nitrogen, oxygen, and two hydrogen atoms. The nitrogen atom is the central atom of the molecule and is connected to the oxygen atom via a double bond. 

This double bond forms the carbonyl group of the molecule. The nitrogen atom is also connected to the hydrogen atoms via single bonds. These single bonds form the amide functional group of the molecule. The structure of N-phenylethanamide can be illustrated in a Lewis structure. 

In this structure, the carbon atom is drawn as the center and the nitrogen, oxygen, and hydrogen atoms are drawn around it. 

The double bond between the nitrogen and oxygen atoms is represented as two dots and a line, while the single bonds between the nitrogen atom and hydrogen atoms are represented as a single line. 

N-phenylethanamide is an important molecule for the synthesis of various pharmaceuticals. In addition, its derivatives are important for the synthesis of dyes, perfumes, and other materials. 

The molecule is also used in the production of various polymers, such as polyethylene terephthalate.

The Physical Properties of n phenylethanamide:

N Phenylethanamide, also known as N-phenylacetamide, is an organic compound with the molecular formula C8H9NO. It is a white crystalline solid with a faint odor and a melting point of 45-47°C. 

It is slightly soluble in water and miscible with most organic solvents. N Phenylethanamide is a cyclic amide, with the amide group linked to the phenyl group. It has a pKa of 8.6, which makes it weakly acidic, and it is relatively unreactive toward strong bases and acids. 

The compound is slightly hygroscopic, meaning it absorbs moisture from the air, but it is not particularly sensitive to water. The compound is insoluble in most non-polar solvents such as hexane, but it is soluble in ethyl acetate. 

It has a low vapor pressure and a low flash point, making it unsuitable for use as a solvent. N Phenylethanamide has a low log Kow of -1.15, which indicates that it is not likely to be bioaccumulated in the environment. It has a low octanol-water partition coefficient (Log P) of -1.43, indicating that it is also not likely to bioaccumulate in aquatic organisms. 

N Phenylethanamide has a relatively low melting point for an amide, which makes it useful for applications requiring a low-temperature process. It is a relatively non-toxic compound, and it is generally considered to be safe for use in the manufacture of pharmaceuticals, food additives, and cosmetics.

The chemical properties of n phenylethanamide: 

N Phenylethanamide is an organic compound with the chemical formula C8H11NO. It is a white to off-white crystalline solid that is odorless and slightly soluble in water. It is a derivative of aniline and is used in a variety of applications. 

N Phenylethanamide is an amide functional group compound. Amides have a wide range of physical and chemical properties that make them useful in a variety of industries. Amides are generally resistant to acid hydrolysis and bases but can be hydrolyzed using strong acid or base catalysts. 

They also have a low vapor pressure and are relatively insoluble in water. N Phenylethanamide is a weak acid, with a pKa of approximately 8.0. This means that it is slightly acidic in aqueous solutions. 

It also has low solubility in water, with a solubility of 0.01 grams per 100 milliliters at 20 degrees Celsius. N Phenylethanamide is an aromatic amide, meaning that it has an aromatic ring structure. This affects the reactivity of the molecule, as aromatic compounds are more stable than other compounds. 

For example, aromatic compounds are less susceptible to oxidation and reduction reactions than other compounds. N Phenylethanamide also has a high melting point. It melts at 135°C, which is higher than many other organic compounds. 

This high melting point makes it useful in a variety of applications, as it can be used in products that need to be heated for processing. 

N Phenylethanamide is a relatively stable compound. It is not easily oxidized or reduced in aqueous solutions, and it is not susceptible to hydrolysis or other chemical reactions. 

It is also relatively non-toxic, making it a safe choice for use in a variety of products.

The Synthesis of N-Phenylethanamide:

N-Phenylethanamide is an organic compound used in the synthesis of pharmaceuticals, agrochemicals, and other materials. It is a white crystalline solid with a melting point of 72-75 °C. 

The synthesis of N-phenylethanamide involves the reaction of an amine and an acid chloride. The reaction begins by heating the amine and acid chloride in an inert atmosphere. This causes the amine to react with the acid chloride to form an intermediate compound, an amide. 

The amide then undergoes an elimination reaction to form the desired product, N-phenylethanamide. In the first step of the synthesis, an anhydrous solvent, such as dichloromethane or acetonitrile, is used to dissolve the amine and acid chloride. 

The reaction is then heated to a temperature between 60-80°C, and stirring is continued until the reaction is complete. The reaction is usually complete within 1-2 hours. 

The resulting N-phenylethanamide can be purified using recrystallization, column chromatography, or other methods. Once purified, the product can be used to synthesize pharmaceuticals, agrochemicals, and other materials. 

N-Phenylethanamide is a useful compound in the synthesis of a variety of materials. It is an important intermediate in the production of pharmaceuticals, agrochemicals, and other materials. 

Its synthesis involves the reaction of an amine and an acid chloride and can be completed in a few hours with the proper reaction conditions.

The Uses of N-Phenylethanamide: 

N-Phenylethanamide (NPEA) is a type of amide molecule that is composed of nitrogen, carbon, and hydrogen atoms. It is an important compound used in many industrial and laboratory applications, including pharmaceuticals and biotechnology. 

In pharmaceuticals, NPEA is an active ingredient in pain relievers, anti-inflammatory drugs, and muscle relaxants. It is also used as an antibacterial agent in topical ointments and creams. Additionally, NPEA is used in the manufacture of certain cosmetics, including sunscreen and skin care products. 

In biotechnology, NPEA has a number of uses, such as in the production of recombinant proteins, antibodies, and other biological molecules. It is also used as an adjuvant to enhance the immune responses of vaccines, as well as to help stabilize vaccine formulations. 

Additionally, NPEA can be used to help improve the efficiency of DNA sequencing and other molecular biology techniques. NPEA is also used in industrial applications, such as in manufacturing plastics and rubber products. 

It is used as a plasticizer to increase the flexibility of plastic and as a catalyst to speed up the curing of rubber. 

Additionally, NPEA is used as a stabilizer in many chemical processes, such as the production of synthetic fibers and other polymers. Finally, NPEA can be used as a biochemical reagent in the laboratory, such as in the synthesis of other amide compounds. 

Additionally, it can be used as a solvent in organic synthesis and as a medium for biochemical reactions.

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